王芳
职称:副主任医师
科室:皮肤科
导师资格:博士生导师
简介:

植根临床进行了十多年的皮肤科临床诊疗工作,对过敏性皮肤病、特应性皮炎、慢性瘙痒、药物过敏等有深刻认识和丰富诊治经验。紧跟医学科学发展潮流,经过国外皮肤科临床观摩和系统科研培训,参与多个临床试验的实施,具备以科学思维解决具体临床问题的能力。开设过敏性皮肤病专科,致力于慢性病程患者的长期诊疗,以先进的理念和科技手段帮助患者实现系统而有效的疾病管理。

出诊时间
专家门诊
周一
Mon
周二
Tue
周三
Wed
周四
Thur
周五
Fri
周六
Sat
周日
Sun
上午
AM
下午
PM
出诊时间以实际为准

医疗特长:

植根临床进行了十多年的皮肤科临床诊疗工作,对过敏性皮肤病、特应性皮炎、慢性瘙痒、药物过敏等有深刻认识和丰富诊治经验。紧跟医学科学发展潮流,经过国外皮肤科临床观摩和系统科研培训,参与多个临床试验的实施,具备以科学思维解决具体临床问题的能力。开设过敏性皮肤病专科,致力于慢性病程患者的长期诊疗,以先进的理念和科技手段帮助患者实现系统而有效的疾病管理。

 

研究方向:

作为研究型临床医生,从临床疾病和现象出发,热爱科学研究,以过敏性皮肤病,尤其是特应性皮炎、慢性瘙痒和药疹为研究方向,研究内容涉及皮肤免疫系统和皮肤神经系统对皮肤屏障和疾病的调节机制,应用最先进的科学技术手段聚焦医学科学前沿,解决临床实际问题。

 

主要教育和工作经历:

教育背景

2002/09– 2007/06,复旦大学,临床医学专业(七年制),学士

2007/07– 2009/06,复旦大学,临床医学(七年制),皮肤病与性病学专业,硕士

2016/09– 2017/06,中山大学,皮肤病与性病学专业,博士

 

工作经历

2009/7– 2013/12,中山大学附属第一医院皮肤科,医师

2014/01– 2018/12,中山大学附属第一医院皮肤科,主治医师

2017/10– 2020/11,WashingtonUniversity School of Medicine in St. Louis,皮肤科、瘙痒研究中心,博士后

2019/01至今,中山大学附属第一医院皮肤科,副主任医师

 

社会兼职:

2019/10-至今,广东省医师协会皮肤科医师分会第四届委员会委员

 

论著:

1.       Wang F, TangH, Xu JH, Kang KF. Activation of the blood coagulation cascade is involved inpatients with chronic urticaria. J Allergy Clin Immunol. 2009; 123(4): 972-973.

2.       Wang F, ChenH, Zhang X. Sister Mary Joseph's nodule derived from lung cancer. Indian J DermatolVenereol Leprol. 2011; 77(5): 609-611.

  1. 王芳,王卓,章星琪,廖绮曼,何定阳,曹光玲,刘涛,韩建德.皮肤结外鼻型NK/T细胞淋巴瘤7例临床与病理分析.中国肿瘤临床.2011; 38(20): 1287-1290.

  2. 王芳,李毓,莫莹,沈晨,杨璐,章星琪. 药疹临床类型和致敏药谱最近七年与过去十年的对比变化.实用医学杂志,2011;27(21): 3932-3934.

5.       Wang F, Li Y,Mo Y, Shen C, Yang L, Zhang X, Cutaneous adverse drug reactions: an 8-yearretrospective study on hospitalized patients in Southern China, Indian JDermatol Venereol Leprol. 2012; 78(4): 488-490.

  1. 王芳,陈木开,陈小红,廖绮曼,韩建德. 26例皮肤溃疡病因分析.皮肤性病诊疗学杂志.2013; 20(6): 408-411.

  2. 王芳,曹光玲,戚世玲,张小婷,章星琪. 钙泊三醇倍他米松软膏治疗慢性湿疹临床疗效观察.临床皮肤科杂志.2014; 43(3): 179-181.

8.       Wang F, He D,Tang X, Zhang X. Chemokine expression in diverse nonimmediate drughypersensitivity reactions: focus on thymus activation-regulated chemokine,cutaneous T-cell-attracting chemokine, and interleukin-10, Ann Allergy AsthmaImmunol. 2014; 113(2): 204-208.

9.       Wang F, ZhouH, Luo DQ, Han JD, Chen MK. Dermatoscopic findings in cutaneous Rosai-Dorfmandisease and response to low-dose thalidomide. J Dtsch Dermatol Ges. 2014;12(4): 350-352.

10.    Wang F, TangXH, Chen MK. Dermoscopic findings of poikiloderma in dyskeratosis congenita. JAm Acad Dermatol. 2014; 71(5): e195-e196.

11.    Wang F, Zhang X, Xia P, Zhang L, Zhang Z. Upregulationof tumor necrosis factor alpha-induced protein 3 interacting protein 1 mRNA inpsoriasis vulgaris. J Dtsch Dermatol Ges. 2015; 13(2): 159-161.

12.    Wang F, ChenX, Wu W, Wang Z, Han J. A case of histiocytic lymphophagocytic panniculitis(Rosai-Dorfman disease) presenting positive autoantibodies. J Dtsch DermatolGes. 2015; 13(4): 334-336.

  1. 吴少宾,岑珊,蔡壬辛,王芳.药疹患者血清CCL17、CCL27、TNF-α及IL-10的测定及其作用探讨.中山大学学报(医学版),2015; 36 (2): 241-244, 256.

14.    Wang F, ZhangX, Xia P, Zhang L, Zhang Z. Enhancement of mRNA expression of survivin andhuman beta-defensin-3 in lesions of psoriasis vulgaris. Eur J Dermatol.2016;26(1):28-33.

15.    Wang F, ZhaoYK, Wang Z, Liu JH, Luo DQ. Erythema Dyschromicm Perstans Response toIsotretinoin. JAMA Dermatol. 2016; 152(7): 841-842.

16.    Luo DQ,Wu HH, Zhao YK, Liu JH, Wang F. Original Research: Different imiquimodcreams resulting in differential effects for imiquimod-induced psoriatic mousemodels. Exp Biol Med (Maywood). 2016; 241(16):1733-1738.

17.    Wang F, ZhouH. White hair, heterochromia iridis and deafness. J Am Acad Dermatol. 2016;74(6):e111-2.

18.    Wang F, CaiR, He D, Zhao Y, Ye Y, Zhang X. Serum IFN-γ-inducible chemokines CXCL9 and CXCL10are elevated in non-immediate drug hypersensitivity reactions. Asian Pac JAllergy Immunol. 2016;34(3):236-241.

19.    ZhaoYK, Wang F, Chen WN, Xu R, Wang Z, Jiang YW, Luo DQ, Han JD. LupusPanniculitis as an Initial Manifestation of Systemic Lupus Erythematosus: A CaseReport. Medicine (Baltimore). 2016; 95(16): e3429.

20.    Wang F, ZhaoYK, Li M, Zhu Z, Zhang X. Trends in culprit drugs and clinical entities incutaneous adverse drug reactions: A retrospective study. Cutaneous and OcularToxicology. 2017;36(4):370-376.

21.    Wang F, ZhaoYK, Luo ZY, Gao Q, Wu W, Rashmi Sarkar, Luo DQ. Aquagenic cutaneous disorders:a review of literature. J Dtsch Dermatol Ges. 2017;15(6):602-608.

22.    Wang F, Ye Y,Luo ZY, Gao Q, Luo DQ, Zhang X. Diverse expression of TNF-α and CCL27 in serumand blister of Stevens–Johnson syndrome/toxic epidermal necrolysis. Clin TranslAllergy. 2018, 8:12.

23.    Wang F, Feng P, Lin Y, Chen X,Xu D, Wang Z, Han J. Human Cutaneous Protothecosis: A Case Report and Review ofCases from Mainland China, Hong Kong, and Taiwan. Mycopathologia.2018;183(5):821-828.

24.    Li Q,Wang C, Zeng K, Peng X, Wang F. AIDS-associated disseminatedtalaromycosis (penicilliosis) marneffei. J Dtsch Dermatol Ges. 2018;16(10):1256-1259.

25.    Wang F, GaoX, Chen X, Tang X, Chen H, Han J. Successful treatment of interstitial lungdisease related to Stevens-Johnson syndrome/toxic epidermal necrolysis overlapwith etanercept: A case report and published work review. J Dermatol.2019;46(11):1035-1038.

26.    Wang F,Morris C, Bodet ND, Kim BS. Treatment of Refractory Chronic Pruritus of UnknownOrigin With Tofacitinib in Patients With Rheumatoid Arthritis. JAMA Dermatol.2019 Sep 18. doi: 10.1001/jamadermatol.2019.2804. [Epub ahead of print]

27.    MeixiongJ, Anderson M, Limjunyawong N, Sabbagh MF, Hu E, Mack MR, Oetjen LK, Wang F,Kim BS, Dong X. Activation of Mast-Cell-Expressed Mas-Related G-Protein-CoupledReceptors Drives Non-histaminergic Itch. Immunity. 2019;50(5):1163-1171.e5.

28.    Wang F, YangTB, Kim BS. The Return of the Mast Cell: New Roles in Neuroimmune Itch Biology.J Invest Dermatol. 2020;140(5):945-951.

29.    Wang F, KimBS. Itch: A Paradigm of Neuroimmune Crosstalk. Immunity. 2020;52(5):753-766.

30.    ClarkM, Wang F, Bodet ND, Kim BS. Evaluation of apremilast in chronicpruritus of unknown origin: A proof-of-concept, phase 2a, open-label,single-arm clinical trial. Health Sci Rep. 2020;3(2):e154. doi:10.1002/hsr2.154.

31.    Gao X,Tang X, Ai L, Gao Q, Liao Q, Chen M, Chen X, Zhou H, Ye Y, Li M, Han J, WangF. Acute pancreatic injuries: A complication of Stevens-Johnsonsyndrome/toxic epidermal necrolysis associated with cytotoxic immune cellactivation. J Am Acad Dermatol. 2020 Jun 16:S0190-9622(20)31140-3. [Epub aheadof print]

32.    MackMR, Brestoff JR, Berrien-Elliott MM, Trier AM, Yang TB, McCullen M, Collins PL,Niu H, Bodet ND, Wagner JA, Park E, Xu AZ, Wang F, Chibnall R, CouncilML, Heffington C, Kreisel F, Margolis DJ, Sheinbein D, Lovato P, Vivier E,Cella M, Colonna M, Yokoyama WM, Oltz EM, Fehniger TA, Kim BS. Blood naturalkiller cell deficiency reveals an immunotherapy strategy for atopic dermatitis.Sci Transl Med. 2020 Feb 26;12(532):eaay1005. doi:10.1126/scitranslmed.aay1005.

33.    Wang F, Trier AM, Li F, Kim S, Chen Z, Chai JN, Mack MR,Morrison SA, Hamilton JD, Baek J, Yang TB, Ver Heul AM, Xu AZ, Xie Z, Dong X,Kubo M, Hu H, Hsieh CS, Dong X, Liu Q, Margolis DJ, Ardeleanu M, Miller MJ, KimBS. A Basophil-Neuronal Axis Promotes Itch. Cell. 2020. In press. Cell SneakPeak 2.0. Available at SSRN: https://ssrn.com/abstract=3624459 or http://dx.doi.org/10.2139/ssrn.3624459.

 

专著:

章星琪,陈木开,陈小红,唐旭华,周晖,马春光,王芳,叶艳婷,戴海蓉,毛壬翔,韩建德,何定阳,高谦,凌宏忠,廖绮曼,曹光玲,李欢,陈闻纳,杨建.色素性和毛发疾病皮肤镜图谱(脂溢性角化,恶性黑素瘤).广东科技出版社,170千字,2014.

 

其他主要工作成绩(比如获奖情况):

先后主持国家自然科学基金两项,广东省自然科学基金三项。

2018年 中华医学会皮肤性病学分会“杰出青年医师奖”前十名候选人。