Departments Department of Neurology

Yu Jian

Chief physician

Overview

Clinical Interests

Neurology; Cerebrovascular Diseases

Medical Education

PhD, MD

Work Experiences

Post-doc training in Northwestern University

1st Affiliated Hospital of Sun Yat-sen University

Biography

Published article in recent five years:

(1) Netrin-1 rescues neuron loss by attenuating secondary apoptosis in ipsilateral thalamic nucleus following focal cerebral infarction in hypertensive rats. Neuroscience, 2013, 231:225

 (2) Inordinate glucose variation poststroke is associated with poor neurological improvement in patients without history of diabetes. CNS Neurosci Ther, 2014, 20(6):503

 (3) Beclin 1 knockdown retards re-endothelialization and exacerbates neointimal formation via a crosstalk between autophagy and apoptosis. Atherosclerosis, 2014, 237(1):146

 (4) Neuroprotective effect of chondroitinase ABC on primary and secondary brain injury after stroke in hypertensive rats. Brain Res, 2014, 1543:324

 (5) Axon guidance factor netrin-1 and its receptors regulate angiogenesis after cerebral ischemia. Neurosci Bull, 30(4):683

 (6) Netrin-1 promotes survival of brain microvessel endothelial cells following oxygen-glucose deprivation associated with enhancement of autophagy. Cerebrovasc Dis, 2015, 39(suppl 2):276

 (6) Netrin-1 ameliorates blood-brain barrier impairment secondary to ischemic stroke via the activation of PI3K pathway. Front Neurosci, 2017, 11:700

 (7) The relationship between exposure to hepatitis B virus and increased atherosclerosis-associated morbidity - a meta-analysis. Kardiol Pol, 2018, 76(1):119